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Peer-reviewed veterinary case report

Hemopathogen infections in dogs and blood donors in Brazil

By da Silva, João Vitor Dos Santos Alves et al.·Published in Pathogens (Basel, Switzerland)·2025·Department of Pathology, Brazil·View original on PubMed

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Original publication title: Molecular Survey of Hemopathogens in Dogs, Including Blood Donors, from Central-Western Brazil.

Species:
dog

Plain-English summary

A study in Brazil found that some dogs who donated blood tested positive for certain blood pathogens, which can be harmful, especially for sick dogs needing transfusions. Out of 100 blood samples from patient dogs, 15% had one type of pathogen, while 5% of blood donor dogs had hemoplasmas, which are tiny bacteria that can affect the blood. This research highlights the importance of testing blood donors to ensure the safety of transfusions and prevent spreading infections to other dogs.

People also search for: dog blood transfusion safety · hemoplasmas in dogs · blood donor dog infections

Abstract

Blood transfusions are indispensable in Veterinary Medicine, providing therapeutic support in cases of hematological disorders. Several pathogens can cause disease and/or exacerbate the condition of immunocompromised dogs or those requiring a transfusion. This study aimed to investigate the molecular occurrence of hemopathogens (spp.,spp.,spp., piroplasmids, and hemoplasmas) in blood donor and patient dogs using samples from a clinical veterinary laboratory in Brazil. One hundred blood samples were collected from each group. All dogs tested negative forspp. in all performed assays. Among the 100 dogs from the clinical veterinary laboratory, 15% (95% CI: 9.3-23.3) tested positive forspp., 6% (95% CI: 2.8-12.5) forspp., 3% (95% CI: 1.0-8.5) forspp., and 2% (95% CI: 0.6-7.0) for hemoplasmas. Blood donor dogs tested positive for hemoplasmas (5%) (95% CI: 2.2-11.2). Additional conventional and real-time PCR assays followed by sequencing confirmed the presence of,,, 'Mycoplasma haematoparvum', and. The molecular detection of,, '. M. haematoparvum', andin dogs from midwestern Brazil reinforces the relevance of molecular tools in diagnosing hemopathogens. This is the first molecular detection of hemoplasmas in canine blood donors from Brazil. This finding indicates their silent circulation and highlights the importance of molecular screening to prevent the worsening of clinical conditions and the risk of turning recipients into new sources of infection.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41305416/