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Peer-reviewed veterinary case report

Monitoring the progression of renal failure in a horse with polycystic kidney disease: use of the reciprocal of serum creatinine concentration and sodium sulfanilate clearance half-time.

Journal:
Journal of the American Veterinary Medical Association
Year:
1987
Authors:
Bertone, J J et al.
Affiliation:
Department of Clinical Sciences · United States
Species:
horse

Plain-English summary

In this case, a horse with chronic kidney failure was diagnosed with polycystic kidney disease, which means it had fluid-filled sacs in its kidneys. The veterinarians used specific blood tests to keep track of how the horse's kidney function was changing over time. They were able to predict when the horse's kidneys would completely stop working based on the test results. This approach helped them monitor the horse's condition more effectively.

Abstract

Sequential reciprocals of serum creatinine concentration and sodium sulfanilate clearance half-times were used to monitor a horse with chronic renal failure. The horse was diagnosed as having polycystic kidney disease; at least one cyst was of distal tubular origin. Using the plots of the sequential data, a reasonably accurate prediction was made for complete renal decompensation to develop.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/3667417/