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Peer-reviewed veterinary case report

Monkeys and Rats Are Not Susceptible to Ferret Hepatitis E Virus Infection.

Journal:
Intervirology
Year:
2015
Authors:
Li, Tian-Cheng et al.
Affiliation:
Department of Virology II · Japan
Species:
rodent

Abstract

Ferret hepatitis E virus (HEV), a novel hepatitis E-like virus, has been identified in ferrets in the Netherlands, Japan, and the US. To determine whether ferret HEV transmits to other animals, we inoculated laboratory rats (Wistar), nude rats (Long-Evans-rnu/rnu), and cynomolgus monkeys with ferret HEV (F4351) by intravenous injection. None of the animals demonstrated a positive sign for virus replication, indicating that rats and monkeys are not susceptible to ferret HEV.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/25925280/