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Peer-reviewed veterinary case report

Monoclonal antibody therapy for PCOS?

Journal:
Cell metabolism
Year:
2025
Authors:
Abbott, David H & Dumesic, Daniel A
Affiliation:
Department of Obstetrics and Gynecology · United States

Abstract

There is no cure for polycystic ovary syndrome (PCOS), only treatment for its highly prevalent reproductive, cardiometabolic, and psychological symptoms. Early signs of PCOS appear during infancy. This enabled Cotellessa et al.to develop and administer neutralizing antibody therapy during infancy in a female mouse model to eradicate PCOS symptomology.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/40466621/