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Peer-reviewed veterinary case report

Cat with purple skin lesions and multiple myeloma diagnosis

By Hickford, F H et al.·Published in Journal of the American Veterinary Medical Association·2000·Department of Clinical Sciences, United States·View original on PubMed

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Original publication title: Monoclonal immunoglobulin G cryoglobulinemia and multiple myeloma in a domestic shorthair cat.

Species:
cat

Plain-English summary

A 13-year-old male domestic shorthair cat was brought to the vet due to fever, loss of appetite, and skin issues, including crusty lesions and purple discoloration on its foot pads and ears. Tests revealed a cryoglobulin in the cat's blood, along with high calcium levels and liver problems. Further examinations showed numerous abnormal plasma cells in the liver and bone marrow, leading to a diagnosis of multiple myeloma (a type of cancer) and cryoglobulinemia. Unfortunately, the cat was euthanized due to the severity of its condition.

People also search for: cat skin problems · cat fever and loss of appetite · multiple myeloma in cats · cryoglobulinemia in cats · cat liver disease symptoms

Abstract

A 13-year-old castrated domestic shorthair cat was examined because of fever, anorexia, and dermatologic lesions. Crusting, erythema, and well-demarcated purple discoloration of the foot pads and the tips of the pinnae, nose, and tail were seen. A white flocculent precipitate was detected in cooled serum. This precipitate dissolved upon rewarming, consistent with a cryoglobulin. Hypercalcemia, high alanine and aspartate aminotransferase activities, thrombocytopenia, and a monoclonal IgG gammopathy were found. Numerous hepatic nodules were detected by means of abdominal ultrasonography. Cytologic evaluation of fine-needle aspirates of the liver and spleen revealed numerous plasma cells, and evaluation of a bone marrow aspirate revealed plasmacytosis. A diagnosis of multiple myeloma and monoclonal IgG cryoglobulinemia was made, and the cat was euthanatized.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11019710/