Peer-reviewed veterinary case report
Dog with one-eye jerking eye movements linked to seizures
By J. M. De Frias et al.·Published in Journal of Veterinary Internal Medicine·2026·View original on Semantic Scholar →
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Original publication title: Monocular ictal nystagmus in a dog: potentially a newly recognized focal seizure phenotype
- Species:
- dog
Plain-English summary
A 3-year-old male neutered toy Chinese crested powderpuff dog was brought to the vet after suddenly becoming less responsive and experiencing severe seizures. During the exam, the vet noticed unusual eye movements, including rapid movement in the left eye and misalignment of the right eye. Tests, including MRI and spinal fluid analysis, showed brain lesions and signs of inflammation, leading to a diagnosis of meningoencephalitis (inflammation of the brain and its surrounding membranes). Unfortunately, despite treatment efforts, the dog did not survive.
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Abstract
Abstract A 3-year-old, male neutered toy Chinese crested powderpuff dog was presented with an acute onset obtundation that progressed to status epilepticus. On presentation, neurological examination was localized to a right forebrain lesion. Bizarre episodes, consisting of disconjugate nystagmus of the left eye, medial strabismus of the right eye with convergent-retraction movements in both eyes, were recorded. Head magnetic resonance imaging revealed intra-axial multifocal lesions affecting the right fronto-temporal cortices and dorsal paramedian thalamus. Cerebrospinal fluid analysis revealed a marked mononuclear pleocytosis. Electroencephalographic recordings revealed recurrent medium-amplitude interictal isolated spikes, and suspected epileptic spikes alongside with eye movement that were mainly visible in the right hemisphere. The presumptive diagnosis was meningoencephalitis of unknown origin. Despite treatment, the dog died. This is a report of monocular nystagmus with a presumptive epileptic origin in veterinary medicine, a rare clinical sign in human patients.
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Search related cases →Original publication on Semantic Scholar: https://www.semanticscholar.org/paper/41742548