Peer-reviewed veterinary case report
Dog with one eye showing retinopathy of prematurity-like retinal
By Sato, Yu et al.·Published in Veterinary ophthalmology·2022·Department of Clinical Sciences and Advanced Medicine, United States·View original on PubMed →
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Original publication title: Monocular retinopathy of prematurity-like retinal vasculopathy in a dog.
- Species:
- dog
Plain-English summary
A dog was found to have serious eye problems in the left eye, including abnormal blood vessels and areas without blood supply. This condition, similar to a disease seen in premature babies called retinopathy of prematurity (ROP), can lead to blindness. Various advanced imaging techniques were used to examine the dog's eye, revealing significant issues with the retinal blood vessels. Although the exact cause of this eye condition in the dog is unknown, it shows that similar vascular problems can occur in dogs even without oxygen therapy. Unfortunately, the outcome for the dog's vision is not mentioned.
People also search for: dog eye problems · retinopathy in dogs · dog vision loss treatment
Abstract
PURPOSE: To describe a case of monocular retinopathy of prematurity (ROP)-like vasculopathy without oxygen supplementation in the dog. METHODS: Fundus photographs (RetCam), spectral-domain optical coherence tomography (sdOCT), confocal scanning laser ophthalmoscopy (cSLO), and fluorescein angiography (FA), as well as postmortem histology and immunohistochemistry (Collagen IV and anti-vWF antibodies), were carried out to characterize the vascular abnormalities. RESULTS: Ophthalmic examination showed peripheral and mid-temporal avascular areas in the tapetal region, neovascularization and abnormally dilated and tortuous retinal vessels in the left eye. sdOCT demonstrated not only cross-sectional views of preretinal fibrovascular proliferation but also extensive proliferation extraretinally into the vitreous. FA emphasized demarcation of vascular and avascular zones with neovascular tufts "popcorns." Histology and immunohistochemistry confirmed presence of abnormally dilated vessels and the intravitreal blood vessels. CONCLUSIONS: ROP is a disease of abnormally developed retinal vascularization associated with oxygen supplementation therapy, potentially causing blindness in premature infants. Although the mechanism of ROP-like vasculopathy in our case is unclear, it is important to appreciate that the abnormal vascular pattern seen in ROP in premature infants can occur in canines without oxygen administration.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34861080/