Peer-reviewed veterinary case report
More than meets the eye: A conserved sensorimotor reflex helps unravel the circuit mechanisms of ASD.
- Journal:
- Neuron
- Year:
- 2024
- Authors:
- Hyde, Romana J & Rudolph, Stephanie
- Affiliation:
- Dominick P. Purpura Department of Neuroscience · United States
Abstract
Animal models are instrumental to understanding the mechanisms underlying autism spectrum disorder, yet translating human behavioral phenotypes remains challenging. Wang et al. leverage a conserved sensorimotor reflex to elucidate synaptic deficits in Scn2a haploinsufficiency and pilot novel rescue strategies.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/38697019/