Peer-reviewed veterinary case report
Liver nodular fibrosis in an 8-year-old male Papillon dog
By Shiga, A et al.·Published in The Journal of veterinary medical science·1996·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Morphological study on a case of canine hepatic nodular fibrosis.
- Species:
- dog
Plain-English summary
An 8-year-old male Papillon was diagnosed with hepatic nodular fibrosis, a condition affecting the liver. The dog had fibrous nodules in the liver that were linked to the portal areas, which are parts of the liver involved in blood flow. The presence of certain cells in the nodules suggests that they may contribute to the development of this condition. Treatment options weren't specified, but understanding the condition can help veterinarians provide appropriate care for affected dogs.
People also search for: dog liver disease symptoms · Papillon liver nodules · canine hepatic fibrosis treatment
Abstract
Hepatic nodular fibrosis occurred in an 8-year-old male Papillon dog. Fibrous nodules, consisting of broad bands of collagen fibers, spindle cells, and lipofuscin-laden foamy macrophages, were well-circumscribed and frequently linked up with the portal areas. Because the spindle cells were positive for desmin and/or alpha-smooth muscle actin, they might be Ito cells or myofibroblasts. These results suggest that both the spindle cells and macrophages play an important role in the pathogenesis of hepatic nodular fibrosis, which might arise from the portal area.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8777242/