Peer-reviewed veterinary case report
Mouse Models for Campylobacter jejuni Colonization and Infection.
- Journal:
- Methods in molecular biology (Clifton, N.J.)
- Year:
- 2017
- Authors:
- Stahl, Martin et al.
- Affiliation:
- Department of Pediatrics · Canada
- Species:
- rodent
Abstract
Relevant animal models for Campylobacter jejuni infection have been difficult to establish due to C. jejuni's inability to cause disease in many common animal research models. Fortunately, recent work has proven successful in developing several new and relevant mouse models of C. jejuni infection, including the SIGIRR-deficient mouse strain that develops acute enterocolitis in response to C. jejuni. Here we describe how to properly infect mice with C. jejuni, as well as a number of accompanying histological techniques to aid in studying C. jejuni colonization and infection in mice.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/27885607/