Peer-reviewed veterinary case report
Mpox therapeutics in the post-STOMP/PALM era.
- Journal:
- Current opinion in HIV and AIDS
- Year:
- 2026
- Authors:
- Promer, Katherine et al.
- Affiliation:
- Department of Medicine · United States
Abstract
PURPOSE OF REVIEW: This article reviews the evidence behind mpox antiviral therapies which are clinically available and/or or under clinical investigation. For much of the mpox epidemic, tecovirimat has been used compassionately but there is no evidence of its clinical efficacy. RECENT FINDINGS: Multiple phase 3 placebo-controlled trials have failed to demonstrate clinical efficacy of tecovirimat in the treatment of mpox. SUMMARY: This article summarizes the evidence behind current treatment recommendations including tecovirimat, brincidofovir, cidofovir, trifluridine, and VIGIV, as well as other investigational treatments.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/41492192/