Peer-reviewed veterinary case report
MRI compatible electrodes for the induction of amygdala kindling in rats.
- Journal:
- Journal of neuroscience methods
- Year:
- 2006
- Authors:
- Jupp, Bianca et al.
- Affiliation:
- The Department of Medicine · Australia
- Species:
- rodent
Abstract
The rat electrical kindling model has been widely utilized in epilepsy research. This study aimed to identify the optimum "MRI compatible" bipolar stimulating and recording electrodes to enable serial MRI acquisition in this model. Two types of custom-made electrodes (gold and carbon) were compared with commercial platinum-iridium alloy electrodes for suitability based on size, effect on image quality and kindling induction. The custom-made gold electrodes, based on these parameters, were found to be most suitable. These electrodes enable the study of epileptogenesis utilizing MRI in this model of temporal lobe epilepsy (TLE).
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/16466802/