Peer-reviewed veterinary case report
MRI shows brainstem and cerebellum gliomatosis cerebri in dog
By Martin-Vaquero, Paula et al.·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2012·Department of Veterinary Clinical Sciences, United States·View original on PubMed →
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Original publication title: MRI features of gliomatosis cerebri in a dog.
- Species:
- dog
Plain-English summary
A 3-year-old dog was experiencing neurological symptoms due to a rare brain condition called gliomatosis cerebri, which affected areas of the brain responsible for movement and coordination. MRI scans showed significant changes in the brain structure, including abnormal areas in the cerebellum, but there were no signs of infection or inflammation in the cerebrospinal fluid. Unfortunately, the dog did not survive, and a postmortem examination confirmed the diagnosis. This case highlights the importance of considering gliomatosis cerebri when a dog shows signs of central nervous system issues.
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Abstract
The features of gliomatosis cerebri involving the brainstem and cerebellum in a 3-year-old dog are described. In magnetic resonance (MR) images, there was diffuse loss of the cerebellar folia and cerebellar gray and white matter contrast. Multiple illdefined T2-hyperintensities were present in the cerebellar parenchyma. A poorly defined, T2-hyperintense mass effect was present ventral to the pons and rostral medulla. No contrast enhancement was noted. Cerebrospinal fluid (CSF) was normal. Postmortem examination was consistent with gliomatosis cerebri, based on compatible histopathology and immunohistochemical findings. Although rare, gliomatosis cerebri should be included as a differential for diffuse infiltrative central nervous system (CNS) lesions.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22413939/