Peer-reviewed veterinary case report
MRI shows brain germ cell tumors in two dogs with neurological signs
By Cook, Laurie et al.·Published in Journal of the American Animal Hospital Association·2018·From the Department of Veterinary Clinical Sciences (L.C., United States·View original on PubMed →
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Original publication title: MRI Findings of Suprasellar Germ Cell Tumors in Two Dogs.
- Species:
- dog
Plain-English summary
A 4-year-old border collie was brought in because its pupils were very dilated and it seemed less alert, while a 7-year-old Boston terrier was showing signs of confusion, a head tilt, and weakness in its back legs. Both dogs underwent MRI scans, which revealed tumors in their brains that were affecting nearby structures. Unfortunately, both dogs had germ cell tumors, a rare type of brain tumor in dogs, and they did not survive. This highlights the importance of early detection and the need for further research on this type of tumor in pets.
People also search for: dog brain tumor symptoms · border collie mydriasis causes · Boston terrier head tilt treatment
Abstract
A 4 yr old border collie presenting for mydriasis and decreased mentation and a 7 yr old Boston terrier presenting for obtundation, head tilt, and paraparesis were both evaluated using MRI. Findings in both included mass lesions of the thalamus and brainstem that were hypo- to isointense on T1-weighted images and hyperintense on T2-weighted images with regions of hypointensity, and robust contrast enhancement and displacement of adjacent structures. Postmortem histopathology findings, tumor location, and a mixed pattern of epithelial cell differentiation were consistent with germ cell tumor in both cases. Germ cell tumor of the suprasellar region is an infrequently reported neoplasm of dogs and imaging findings in this species have not been well described in the prior literature.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29558220/