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Peer-reviewed veterinary case report

MRI Findings of Suprasellar Germ Cell Tumors in Two Dogs.

Journal:
Journal of the American Animal Hospital Association
Year:
2018
Authors:
Cook, Laurie et al.
Affiliation:
From the Department of Veterinary Clinical Sciences (L.C. · United States
Species:
dog

Plain-English summary

Two dogs, a 4-year-old border collie and a 7-year-old Boston terrier, were diagnosed with brain tumors after undergoing MRI scans. The border collie showed signs of dilated pupils and confusion, while the Boston terrier had a decreased level of alertness, a tilt of the head, and weakness in its back legs. The MRI revealed abnormal growths in areas of the brain that control important functions, and both tumors were identified as germ cell tumors, which are rare in dogs. Unfortunately, both dogs had serious conditions that were confirmed after they passed away.

Abstract

A 4 yr old border collie presenting for mydriasis and decreased mentation and a 7 yr old Boston terrier presenting for obtundation, head tilt, and paraparesis were both evaluated using MRI. Findings in both included mass lesions of the thalamus and brainstem that were hypo- to isointense on T1-weighted images and hyperintense on T2-weighted images with regions of hypointensity, and robust contrast enhancement and displacement of adjacent structures. Postmortem histopathology findings, tumor location, and a mixed pattern of epithelial cell differentiation were consistent with germ cell tumor in both cases. Germ cell tumor of the suprasellar region is an infrequently reported neoplasm of dogs and imaging findings in this species have not been well described in the prior literature.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/29558220/