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Peer-reviewed veterinary case report

mRNA-based monkeypox virus vaccine prevents disease in non-human primates.

Journal:
Cell
Year:
2024
Authors:
Nitido, Adam N & Balazs, Alejandro B
Affiliation:
Ragon Institute of MGH · United States

Abstract

The mpox outbreak in 2022 launched a vaccination campaign employing an existing vaccine with moderate protection, highlighting the lack of scalable Orthopoxvirus vaccines with optimal protection. In this issue of Cell, Zuiani et al. report pre-clinical findings of an mRNA-based mpox vaccine, paving the way for Phase I/II clinical trials.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/38490180/