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Peer-reviewed veterinary case report

mRNA vaccines: A promising platform for safer, more effective next-generation Orthopoxvirus immunization.

Journal:
Cell host & microbe
Year:
2024
Authors:
Han, Xiaonan et al.
Affiliation:
Institute of Microbiology · China

Abstract

In recent work, Mucker et al.demonstrated that mRNA-1769 outperforms modified vaccinia Ankara (MVA), which has been deployed against recent mpox virus (MPXV) outbreaks, in reducing clinical symptoms and controlling viral replication, highlighting its potential as a scalable, safe, and effective next-generation platform for orthopoxvirus vaccination.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/39541944/