Peer-reviewed veterinary case report
Dog with mucinous stomach cancer and high gastrin levels
By de Brito Galvao, Joao F et al.·Published in Journal of the American Animal Hospital Association·2009·School of Veterinary Medicine, United States·View original on PubMed →
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Original publication title: Mucinous gastric carcinoma with abdominal carcinomatosis and hypergastrinemia in a dog.
- Species:
- dog
Plain-English summary
A 12-year-old spayed female Australian cattle dog was brought in for vomiting that had been getting worse over the past five months. Tests showed thickening of the stomach wall and a mass near the pancreas, along with high levels of a hormone called gastrin. During surgery, the vet found cancer in the stomach and other areas, but sadly, the dog faced severe complications afterward and had to be euthanized ten days later. This case highlights a rare type of stomach cancer in dogs that was linked to high gastrin levels.
People also search for: dog vomiting treatment · Australian cattle dog stomach cancer · high gastrin levels in dogs
Abstract
A 12-year-old, spayed female Australian cattle dog was evaluated for a 5-month history of progressive vomiting. Abdominal radiographs and ultrasound revealed significant gastric wall thickening and a peripancreatic mass, and serum gastrin concentration was increased (127 pg/mL, reference range 10 to 40 pg/mL). Surgical exploration of the abdomen revealed a thickened, firm, and irregular gastric fundus, pylorus, and antrum; nodules were present throughout the spleen and mesentery adjacent to the left limb of the pancreas. Mucinous gastric carcinoma with carcinomatosis was diagnosed by histopathological examination of surgically excised tissues. Unfortunately, severe postoperative complications resulted in euthanasia 10 days after surgery, and a necropsy was not performed. This case is significant, because it is the first report of a mucinous gastric carcinoma associated with hypergastrinemia in a dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19570904/