Peer-reviewed veterinary case report
Blood culture testing and results in 701 dogs across multiple clinics
By Ogrodny, Andrzej J et al.·Published in Frontiers in veterinary science·2023·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Multi-institutional retrospective study investigating blood culture protocols and test positivity in 701 dogs.
- Species:
- dog
Plain-English summary
A study involving 701 dogs found that those with a positive urine culture were more likely to also have a positive blood culture, indicating a potential infection. The research suggested that collecting three blood samples increased the chances of detecting an infection, although this wasn't definitively proven. Interestingly, many of the bacteria found in the blood were resistant to multiple antibiotics. This information can help veterinarians better understand how to diagnose and treat infections in dogs, especially when urine tests show a problem.
People also search for: dog blood infection treatment · positive urine culture in dogs · antibiotic resistance in dogs
Abstract
OBJECTIVES: (i) To determine the influence of specimen collection protocol (timing and specimen quantity), primary disease process, and pre-existing antimicrobial or immunosuppressive therapy on blood culture (BC) positivity and (ii) To determine agreement between urine culture and BC results. ANIMALS: 701 client-owned dogs. METHODS: Multi-institutional retrospective study (2019-2022). Mixed-effect logistic regression was used to determine whether primary disease process, the number of BCs, or the timing of specimen collection was associated with BC positivity. Prediction plots were generated. Associations between urine culture and BC results were performed using logistic regression. RESULTS: Dogs with a positive urine culture were more likely to have a positive BC (OR: 4.36, 95% CI: 2.12-8.97,= 0.003). Dogs that had three BC specimens had the greatest odds of obtaining a positive BC result (adjusted predictive value: 0.44, 95% CI: 0.21-0.70), although this was not significant. Isolates from 38.5% of dogs with a positive BC had resistance to ≥3 antimicrobial classes. The timing between specimen collection had no significant association with BC positivity. Pre-existing antibiotic or immunosuppressive therapy had no significant association with BC positivity. CLINICAL RELEVANCE: Dogs with a positive urine culture were more likely to have a positive BC result.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38152597/