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Peer-reviewed veterinary case report

Multi-modality imaging of aggressive submural neoplasia of the hoof in two horses.

Journal:
Australian veterinary journal
Year:
2022
Authors:
Nagel, H et al.
Affiliation:
REC Equine Specialists · United Kingdom
Species:
horse

Plain-English summary

This study looked at two horses with serious tumors in their hooves. One was a 20-year-old Quarter horse gelding, and the other was a 10-year-old Thoroughbred gelding. Both horses had been diagnosed with aggressive types of cancer: one had anaplastic sarcoma and the other had squamous cell carcinoma. The researchers used various imaging techniques to better understand the lameness these horses were experiencing and to see how the tumors affected the bones and surrounding hoof structures. While advanced imaging can help in figuring out what might be wrong and planning surgery, getting a tissue sample is still essential for a clear diagnosis.

Abstract

This case series presents a 20-year-old Quarter horse gelding and a 10-year-old Thoroughbred gelding with a histologic diagnosis of aggressive submural neoplasia, including an anaplastic sarcoma and a squamous cell carcinoma respectively. The current case series describes these neoplasias with radiography, computed tomography, magnetic resonance imaging and histopathology with immunohistochemistry. The purpose of this case series is to identify the clinical pattern of chronic reoccurring lameness in these cases and highlight the appearance of expansile osteolytic pathology of the distal phalanx with adjacent hoof wall abnormalities. Advanced imaging has the potential to assist with a differential diagnosis list and surgical planning in patients such as these however obtaining a cellular sample for histopathological examination remains necessary for definitive diagnosis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/35781224/