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Peer-reviewed veterinary case report

Dog with multiple muscle tumors in tongue and mouth

By Brockus, C W & Myers, R K·Published in Veterinary pathology·2004·Department of Veterinary Pathology, United States·View original on PubMed

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Original publication title: Multifocal rhabdomyosarcomas within the tongue and oral cavity of a dog.

Species:
dog

Plain-English summary

A 10-year-old terrier crossbreed was brought to the vet because it had been barking differently and panting heavily for 3-4 months. Upon examination, the vet found four masses in the dog's mouth, with the largest one located at the back of the tongue. Tests revealed that these masses were rhabdomyosarcomas, a type of cancer that affects muscle tissue. Unfortunately, due to the nature of the diagnosis, treatment options may be limited, and the prognosis can vary depending on the extent of the disease.

People also search for: dog mouth tumor · terrier cancer symptoms · panting dog with oral masses

Abstract

A 10-year-old terrier crossbreed presented with a change in bark intonation of 3-4 month's duration and pronounced panting. Four variably sized masses were observed within the oral cavity. The largest mass was located within the parenchyma at the caudal region of the tongue. Others were located on the left arytenoid, within the soft palate, and in the oropharynx above the soft palate. Histopathologic specimens consisted of large round to polygonal cells occasionally containing multiple nuclei and rare faint cytoplasmic cross striations. Staining was weakly positive with periodic acid-Schiff. Immunocytochemistry was strongly diffusely positive for muscle-specific actin, myoglobin, and desmin and scattered positive for S-100 and vimentin. Phosphotungstic acid-hematoxylin staining enhanced cytoplasmic cross striations. The cytoplasm of all neoplastic cells was filled with mitochondria on electron microscopy. The final diagnosis was multifocal/metastatic rhabdomyosarcoma.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15133177/