Peer-reviewed veterinary case report
Dog with widespread skin papillomas treated with surgery and cream
By Levy, Britt J et al.·Published in Veterinary dermatology·2018·Department of Medical Sciences, United States·View original on PubMed →
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Original publication title: Multimodal treatment of a dog with disseminated cutaneous viral papillomatosis.
- Species:
- dog
Plain-English summary
An eight-month-old female mixed breed dog was brought in with severe skin problems caused by canine papillomavirus, which had rapidly worsened over two months. She was very itchy, had a bad smell, and the growth of lesions affected her movement and vision, making her quality of life poor. The vet performed surgery to remove some of the lesions and then treated her with a topical cream and an experimental vaccine. After 10 weeks, most of the lesions were gone, and 10 months later, she was completely free of any skin issues.
People also search for: dog skin problems papillomavirus treatment · itchy dog lesions · mixed breed dog skin infection · dog papillomatosis vaccine · dog surgery for skin growths
Abstract
BACKGROUND: Canine papillomaviruses (CPVs) are associated with varied cutaneous manifestations. Spontaneous resolution typically occurs within one to 12 months. This case report describes multimodal treatment of a dog with severe disseminated papillomatosis. CLINICAL SUMMARY: An eight-month-old, female spayed, mixed breed dog was presented with a two month history of rapidly progressing papillomatosis and lack of response to oral azithromycin therapy. The dog was severely pruritic and malodorous; the weight and growth of lesions had progressed to affect the dog's gait and vision, and led to decreased quality of life. The dog was treated with substantial surgical debulking of lesions, followed by daily topical 5% imiquimod cream applied to nonexcisable lesions, and received five doses of an experimental recombinant CPV2 L1 vaccine every 14 days for 10 weeks. At the end of the 10 weeks, two lesions remained and were excised. No additional treatment was needed and 10 months post-treatment the dog was lesion free. CONCLUSION: New therapies need to be developed and assessed, in controlled treatment trials, to determine the efficacy of single modality therapeutic interventions for severe, persistent canine cutaneous papillomatosis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28921687/