Peer-reviewed veterinary case report
Blindness and brain tumor with skull defects in a dog
By Hughes, Jonathan R et al.·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2021·Queen's Veterinary School Hospital, United Kingdom·View original on PubMed →
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Original publication title: Multimodality characteristics of multifocal choroid plexus carcinoma with bilateral calvarial defects in a dog.
- Species:
- dog
Plain-English summary
An 8-year-old male miniature poodle was brought in because he was blind, lethargic, and had trouble moving his legs. Tests like MRI and ultrasound showed brain lesions and fluid buildup, along with skull defects. A biopsy confirmed he had a choroid plexus carcinoma, a type of brain cancer, which had spread to other areas. Unfortunately, due to the severity of his condition, treatment options were limited, and the prognosis was poor.
People also search for: dog blindness causes · miniature poodle brain cancer symptoms · dog tetraparesis treatment
Abstract
An 8-year-old male intact miniature poodle presented for blindness, obtundation, tetraparesis, and vestibular signs. Magnetic resonance imaging, radiography, and ultrasound revealed a left piriform lobe lesion, right cerebellar and left brainstem lesions, and hydrocephalus and bilateral calvarial defects. Histopathology confirmed a choroid plexus carcinoma with meningeal and intraventricular metastases. The calvarial defect did not show evidence of necrosis, osteoclastic resorption, inflammation or neoplastic infiltration, reflecting a quiescent calvarial atrophy or dysplasia. These novel findings supported inclusion of bone atrophy secondary to chronic increased intracranial pressure as a differential diagnosis for large calvarial defects in dogs with choroid plexus carcinoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30892784/