Peer-reviewed veterinary case report
Multiple endocrine diseases diagnosed in 35 dogs from 1996-2009
By Blois, Shauna L et al.·Published in Journal of the American Veterinary Medical Association·2011·Department of Clinical Studies and Ontario Veterinary College Teaching Hospital, Canada·View original on PubMed →
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Original publication title: Multiple endocrine diseases in dogs: 35 cases (1996-2009).
- Species:
- dog
Plain-English summary
A group of 35 dogs, mostly Miniature Schnauzers, were found to have two or more endocrine disorders, with the average age at diagnosis being about 8 years. Many of these dogs had diabetes and hyperadrenocorticism (Cushing's disease), while others had combinations like hypoadrenocorticism (Addison's disease) and hypothyroidism. On average, it took about 14 months for a second disorder to be diagnosed after the first one. While having multiple endocrine disorders is rare in dogs, the study highlights the importance of monitoring for additional health issues once one is identified.
People also search for: dog diabetes treatment · Cushing's disease in dogs · Miniature Schnauzer endocrine disorders
Abstract
OBJECTIVE: To characterize a population of dogs from a tertiary care center with 2 or more endocrine disorders, including the specific disorders and time intervals between diagnosis of each disorder. DESIGN: Retrospective case series. ANIMALS: 35 dogs with 2 or more endocrine disorders. PROCEDURES: Medical records were reviewed, and the following was recorded: clinical signs, physical examination findings, and the results of CBC, serum biochemical analysis, urinalysis, aerobic bacterial culture of urine samples, endocrine testing, diagnostic imaging, and necropsy. RESULTS: 35 dogs with more than 1 endocrine disorder were identified. Seventy-seven percent (27/35) of the dogs were male, and the mean age at the time of diagnosis of the first endocrinopathy was 7.9 years. Miniature Schnauzer was the most common breed. Twenty-eight of 35 (80%) dogs had 2 disorders; 7 (20%) had 3 disorders. The most common combinations of disorders included diabetes mellitus and hyperadrenocorticism in 57.1 % (20/35) of dogs; hypoadrenocorticism and hypothyroidism in 22.9% (8/35) of dogs; and diabetes mellitus and hypothyroidism in 28.6% (10/35) of dogs. A mean of 14.5 months elapsed between diagnosis of the first and second endocrine disorders, whereas there was a mean of 31.1 months between diagnosis of the first and third endocrine disorders. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggested that the occurrence of multiple endocrine disorders was uncommon in dogs. The most common combinations of endocrine disorders in this population of dogs were diabetes mellitus and hyperadrenocorticism, followed by hypoadrenocorticism and hypothyroidism.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21671817/