Peer-reviewed veterinary case report
Cat with hair loss and skin thickening from follicular growths
By Moog, Fabien et al.·Published in Veterinary dermatology·2022·Small Animal Clinic, France·View original on PubMed →
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Original publication title: Multiple follicular abnormalities in a 1-year old cat consistent with basaloid follicular hamartomas.
- Species:
- cat
Plain-English summary
A 1-year-old neutered domestic short hair cat was brought in for hair loss and unusual skin markings on its belly, chest, and legs. The cat had multiple skin growths that were causing thickening around its face and feet. After examining skin samples, the veterinarian found that these growths were benign follicular tumors called basaloid follicular hamartomas. Fortunately, these tumors are not harmful, and while the cat may need monitoring, there are no immediate treatments required.
People also search for: cat hair loss treatment · cat skin growths · domestic short hair skin problems
Abstract
BACKGROUND: In humans, basaloid follicular hamartomas are benign follicular tumours, that can be solitary or multiple, in which case they show autosomal dominant inheritance. HYPOTHESIS/OBJECTIVES: This study describes clinical and histopathological findings observed in a young cat, which could be consistent with basaloid follicular hamartomas. CASE DESCRIPTION: Multiple follicular abnormalities, consistent with cutaneous diffuse basaloid follicular hamartomas, were observed in skin samples from a one-year old neutered domestic short hair cat. Clinical signs were diffuse symmetrical alopecia with exaggerated skin markings (ventral abdomen, thorax and medial aspects of the limbs) and intense follicular-centred thickening (face and feet). Microscopic lesions were characterised by multiple proliferative follicular abnormalities in all samples. The epidermis showed a very irregular surface with the follicles filled with variably pigmented keratin. The epithelial walls of the follicles had multiple small hyperplastic basaloid cells foci. In the superficial dermis under the epidermis and around the follicles, fibroblastic spindle-shaped mesenchymal cells with a homogeneous moderate density were present in the collagenous connective tissue. The interfollicular epidermis was also abnormal with multiple small proliferating trichoblastic foci originating from the basal layer. RNAscope testing for feline papillomavirus was negative. CONCLUSIONS AND CLINICAL RELEVANCE: This case report provides the first evidence of clinical and histopathological findings of multiple follicular abnormalities, consistent with cutaneous diffuse basaloid follicular hamartomas in a cat.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35297135/