Peer-reviewed veterinary case report
Multiple tongue nodules in miniature dachshund dogs explained
By Katou-Ichikawa, C et al.·Published in Veterinary pathology·2016·Department of Veterinary Science, Japan·View original on PubMed →
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Original publication title: Multiple Histiocytic Foam Cell Nodules in the Tongue of Miniature Dachshund Dogs.
- Species:
- dog
Plain-English summary
A group of seven Miniature Dachshund dogs was brought in with multiple lumps on their tongues, mainly on the underside and sides. Some dogs also had growths in their mouths, and three of them had these lumps come back after surgery to remove them. The lumps were made up of special cells called foam cells, which are related to the immune system. This condition is unusual and doesn't match other known tongue problems in dogs. Treatment involved surgical removal, but some dogs experienced recurrences.
People also search for: Miniature Dachshund tongue lumps · dog oral masses treatment · why does my dog have lumps on tongue
Abstract
Miniature dachshund dogs are a common breed in Japan and are known to be predisposed to granulomatous diseases. Here we report the pathologic features of multiple lingual nodules in 7 miniature dachshunds. Seven dogs had multiple nodules of variable sizes mainly on the ventral and lateral surface of the tongue. In addition, 1 dog also had masses on the left oral mucosa. Three cases had recurrence after surgical resection. Histologically, the lingual nodules were composed of aggregates of foam cells with clear vacuolated cytoplasm that were negative for oil red O, PAS, and alcian blue. They stained positively for CD204 (macrophage scavenger receptor) and MHC class II and negatively for Iba-1, E-cadherin, adipophilin, cytokeratins, S-100, and nestin. These findings indicate that the multiple lingual nodules in miniature dachshunds are an unusual, unique lesion consisting of macrophage-derived foam cells, which does not correspond to canine lingual diseases reported to date.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26173452/