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Peer-reviewed veterinary case report

Dog diagnosed with multiple myeloma and high red blood cells

By Ricci, Marianna et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2021·Department of Veterinary Science, Italy·View original on PubMed

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Original publication title: Multiple myeloma and primary erythrocytosis in a dog.

Species:
dog

Plain-English summary

A 13-year-old spayed female mixed breed dog was brought in because she was having trouble walking, had tremors in her limbs, and was experiencing back pain. The vet found that her blood was unusually thick and red, and tests showed she had multiple myeloma (a type of bone cancer) along with severe primary erythrocytosis (an increase in red blood cells). This combination of conditions is rare in dogs. Unfortunately, the outcome of the treatment is not specified, but it's important for pet owners to be aware that these serious health issues can occur together in dogs.

People also search for: dog back pain · dog tremors · multiple myeloma in dogs · dog red blood cell increase · dog cancer treatment options

Abstract

A 13-year-old spayed female mixed breed dog was referred for impaired ambulation, limb tremors, back pain, hypergammaglobulinemia on cellulose acetate electrophoresis, and mild proteinuria. Conventional radiology and magnetic resonance imaging (MRI) suggested multifocal neoplastic bone lesions. At the referral examination, lameness and bright red mucous membranes were observed. Severe erythrocytosis, a monoclonal peak in the β-2 globulin detected by capillary zone electrophoresis, severe proteinuria, bone marrow infiltration of plasma cells, and low serum erythropoietin concentrations were reported. The final diagnosis was multiple myeloma associated with severe primary erythrocytosis. This presentation in a dog is interesting because the combination of both disorders is rare in humans and has not been reported in dogs. Key clinical message: Although rare, multiple myeloma and primary erythrocytosis can occur together in dogs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34341597/