Multiple ophthalmic abnormalities in an infant rhesus macaque (Macaca mulatta).

Abstract

BACKGROUND: A 4.5-month-old male colony-bred Indian rhesus macaque was presented for presumed trauma to the right eye. The globe was centrally distended 5 mm, with apparent hyphema and moderate to severe corneal edema. Surgical enucleation was performed. The initial histopathology report concluded chronic keratitis. Nearly 3 years later, a diagnosis of goniodysgenesis was made. The eye was sent to a veterinary ocular pathologist for definitive diagnosis. CONCLUSIONS: Final conclusions were anterior segment and corneal defects. Based on the retinal pathology and optic nerve pathology, there was evidence of optic nerve atrophy, a recently described condition in macaques.