Peer-reviewed veterinary case report
Dog with carotid body tumor spreading to multiple bones
By Okajima, Mina et al.·Published in The Journal of veterinary medical science·2007·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Multiple osseous metastases of a carotid body tumor in a dog.
- Species:
- dog
Plain-English summary
A 13-year-old female Siberian husky was brought in with hind limb paralysis, which was found to be caused by a malignant carotid body tumor that had spread to multiple bones. X-rays showed an abnormal mass in the throat area and damage to the spine, tibia, and ribs. Sadly, the dog had multiple tumors in the bones and surrounding areas, and the diagnosis confirmed the cancer had metastasized. Unfortunately, due to the advanced stage of the disease, treatment options were limited, and the prognosis was poor.
People also search for: Siberian husky hind limb paralysis · dog carotid body tumor symptoms · dog bone cancer treatment
Abstract
Metastasis of malignant carotid body tumor to multiple bones was detected in a 13-year-old female Siberian husky dog. Radiographs exhibited an abnormal mass in the retropharyngeal site and osteolytic lesions in the vertebral bodies, spinous process, tibia, and ribs. At necropsy, multiple masses were observed in the bones as well as at the dorsal area of the retropharynx. Histologically, the tumor cells, arranged in sheets and clusters, had eosinophilic finely granular cytoplasm. Immunohistochemistry showed the tumor cells were positive for neuron-specific enolase and synaptophysin. Electron microscopy demonstrated a number of dense membrane-bound granules in the cytoplasm of the tumor cells. Based on these findings, this case was diagnosed as multiple bone metastases of a malignant carotid body tumor. Spinal cord damage induced by the tumor mass was the cause of the hind limb paralysis of the present dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17409648/