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Peer-reviewed veterinary case report

Multisystemic eosinophilic epitheliotropic disease in a horse: attempted treatment with hydroxyurea and dexamethasone.

Journal:
The Veterinary record
Year:
1992
Authors:
Hillyer, M H & Mair, T S
Affiliation:
Department of Veterinary Medicine · United Kingdom
Species:
horse

Plain-English summary

This case discusses a rare condition in horses called multisystemic eosinophilic epitheliotropic disease, which affects multiple organs, including the skin and digestive system. The horse in this study showed symptoms related to the skin, liver, lungs, and pancreas. The treatment involved using a corticosteroid and a medication called hydroxyurea, which led to some improvement in the horse's condition. Overall, the treatment partially worked, helping the horse feel better.

Abstract

Equine multisystemic eosinophilic epitheliotropic disease is rare in horses. The clinical signs vary according to the organs affected, the skin and gastrointestinal tract being most commonly involved. This paper gives the first reported description of a horse with multisystemic eosinophilic epitheliotropic disease in the United Kingdom and the attempts to treat it. The horse showed dermatological, gastrointestinal, hepatic, pulmonary and pancreatic involvement. Some improvement was seen when the horse was treated with corticosteroid and hydroxyurea.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/1609466/