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Peer-reviewed veterinary case report

Murine model captures evolution of edema in experimental cerebral malaria.

Journal:
Trends in parasitology
Year:
2024
Authors:
Taylor, Terrie E
Affiliation:
Department of Osteopathic Medical Specialties · United States

Abstract

A complex series of studies by Oelschlegel et al. in a murine model of cerebral malaria establishes a temporal sequence of events linking decreased venous efflux to impaired perfusion, edema, and neuroinflammation. The relevance to human cerebral malaria is discussed, including the heterogeneity recognized in recent investigations of cerebrovascular hemodynamics.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/38797655/