Peer-reviewed veterinary case report
Mus musculus Papillomavirus 1: a New Frontier in Animal Models of Papillomavirus Pathogenesis.
- Journal:
- Journal of virology
- Year:
- 2020
- Authors:
- Spurgeon, Megan E & Lambert, Paul F
- Affiliation:
- Department of Oncology · United States
Abstract
Animal models of viral pathogenesis are essential tools in human disease research. Human papillomaviruses (HPVs) are a significant public health issue due to their widespread sexual transmission and oncogenic potential. Infection-based models of papillomavirus pathogenesis have been complicated by their strict species and tissue specificity. In this Gem, we discuss the discovery of a murine papillomavirus, Mus musculus papillomavirus 1 (MmuPV1), and how its experimental use represents a major advancement in models of papillomavirus-induced pathogenesis/carcinogenesis, and their transmission.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/32051276/