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Peer-reviewed veterinary case report

Muscle and nerve biopsy.

Journal:
The Veterinary clinics of North America. Small animal practice
Year:
2002
Authors:
Dickinson, Peter J & LeCouteur, Richard A
Affiliation:
Department of Surgical and Radiological Sciences · United States

Plain-English summary

Muscle and nerve biopsies are important tests for diagnosing neuromuscular diseases in animals. This article explains how to perform these biopsies, including where to take the samples from and how to handle them properly. It also describes what healthy and unhealthy muscle and nerve tissues look like under a microscope, focusing on the typical responses of the neuromuscular system to different conditions. Overall, the information provided can help veterinarians better understand and diagnose issues related to muscle and nerve health in pets.

Abstract

Biopsy of muscle and nerve is an essential component of the diagnostic plan for animals with suspected neuromuscular disease. This article includes descriptions of the biopsy procedures and information regarding appropriate biopsy site selection and correct handling and processing of the tissues. The normal and pathological appearance of muscle and nerve using routine histochemical and histological techniques are described and illustrated emphasizing the basic myopathic and neuropathic responses of the neuromuscular system.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/11785735/