Peer-reviewed veterinary case report
Cat with stiff walk and muscle disease causing regurgitation
By Kohn, B et al.·Published in Tierarztliche Praxis·1993·Veterinä·View original on PubMed →
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Original publication title: [Muscular dystrophy in a cat].
- Species:
- cat
Plain-English summary
A 1-year-old male Domestic Shorthair cat was brought in for regurgitation, a stiff walk, and trouble exercising. Tests showed high levels of a muscle enzyme called creatine kinase, indicating muscle damage. The cat was diagnosed with muscular dystrophy, a condition that affects muscle strength and function. Unfortunately, this condition is serious and can lead to ongoing muscle problems. Treatment options are limited, but supportive care can help manage symptoms and improve quality of life.
People also search for: cat regurgitation stiff walk · muscular dystrophy in cats · cat exercise intolerance treatment
Abstract
A case of muscular dystrophy in a 1-year-old male castrated Domestic Shorthair cat is presented. The most striking clinical features were regurgitation, a stiff gait, an increased muscle tone and exercise intolerance. Serum biochemistry panels showed a marked increase in the muscle specific enzyme creatine kinase, and moderately elevated levels of LDH, AST and ALT. Spontaneous electrical activity of skeletal muscles in the form of "bizarre high frequency discharges" and "myotonia-like repetitive discharges" were registered. Gross pathology revealed a marked hypertrophy of the skeletal muscles. The main histopathological changes were myofiber necrosis and calcification, variation in fiber size, hypertrophied muscle fibers of type I and type II and fiber splitting. Indirect immunofluorescence showed dystrophin deficiency. Feline muscular dystrophy resembles the X-linked human Duchenne muscular dystrophy (DMD). Besides the X-linked muscular dystrophy in the mouse and Golden Retriever the feline muscular dystrophy could represent another valuable animal model for the study of DMD.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8248906/