Peer-reviewed veterinary case report
Beagle puppy walking on tiptoes with stiff joints and thick fur
By Carneiro, R K et al.·Published in Topics in companion animal medicine·2022·Department of Veterinary Surgery, Brazil·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Musladin-Lueke Syndrome in a Dog: Case Report.
- Species:
- dog
Plain-English summary
A 4-month-old Beagle was brought to the vet because it was walking on its toes and had stiff legs. The vet noticed thick fur, changes in the dog's heart structure, and other unusual features. After testing, the dog was diagnosed with Musladin-Lueke syndrome, a rare genetic condition. Fortunately, the dog was monitored for two years and maintained a good quality of life despite the diagnosis.
People also search for: Beagle walking on toes · Musladin-Lueke syndrome in dogs · dog heart problems symptoms
Abstract
The aim of this study is to report the case of a 4-month-old Beagle dog diagnosed with Musladin-Lueke syndrome. The dog appeared to walk on the digits ("tiptoes") with all limbs during ambulation and rigid extension of the carpus, elbow, tarsus, and knee joints during ambulation. Thickening of the fur and auricular cartilage, reduction in radiocarpal, and tibiotarsal joint amplitude, macrocephaly, and lateralized eyes were noticed on physical examination. Echocardiography showed reduced mobility and altered (tortuous) valve morphology. Bilateral abdominal cryptorchidism was confirmed by ultrasonography. Musladin-Lueke syndrome was the presumptive diagnosis, based on the clinical signs presented. The diagnosis was confirmed after DNA testing performed by serial collection of saliva. This is the first paper that describes unprecedented cardiac and reproductive changes of Musladin-Lueke syndrome in which the dog was followed for 2 years, presenting a good quality of life.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35850448/