Peer-reviewed veterinary case report
Mycobacterium DNA detection in liver and skin of a horse with generalized sarcoidosis.
- Journal:
- Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
- Year:
- 2012
- Authors:
- Oliveira-Filho, José P et al.
- Affiliation:
- Department of Veterinary Clinical Science · Brazil
- Species:
- horse
Plain-English summary
A 16-year-old American Quarter Horse gelding was diagnosed with a rare skin disease called sarcoidosis, which causes severe skin irritation and inflammation. In this case, the horse showed signs of this condition not just in the skin but also in the liver. Tests revealed the presence of Mycobacterium DNA, which might be linked to the development of sarcoidosis in horses, similar to what has been suggested for humans. The findings suggest that Mycobacterium could be involved in causing this disease in horses.
Abstract
Sarcoidosis is a rare equine skin disease characterized primarily by an exfoliative and granulomatous dermatitis but also presenting granulomatous inflammation of multiple systems. The current report presents the clinical and histopathological findings of sarcoidosis in a 16-year-old American Quarter Horse gelding with nested polymerase chain reaction Mycobacterium spp. DNA detection within hepatic and skin samples. Mycobacterium spp. may play a role in the pathogenesis of equine sarcoidosis as has been proposed for human sarcoidosis.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22529133/