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Peer-reviewed veterinary case report

Dilated cardiomyopathy linked to low heart L-carnitine in dogs

By Keene, B W et al.·Published in Journal of the American Veterinary Medical Association·1991·Department of Medical Sciences·View original on PubMed

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Original publication title: Myocardial L-carnitine deficiency in a family of dogs with dilated cardiomyopathy.

Species:
dog

Plain-English summary

A family of dogs with dilated cardiomyopathy (a heart condition) was found to have low levels of L-carnitine, a nutrient important for heart health. Two of these dogs were given high doses of L-carnitine, which significantly improved their heart function and overall health. However, when the L-carnitine was stopped, the dogs' heart problems returned. This suggests that L-carnitine supplementation can be beneficial for dogs with this condition.

People also search for: dog dilated cardiomyopathy treatment · L-carnitine for dogs heart health · symptoms of heart problems in dogs

Abstract

Dilated cardiomyopathy in a family of dogs was found to be associated with decreased myocardial L-carnitine concentrations, when compared with those in control dogs. In 2 affected dogs, treatment with high doses of L-carnitine was associated with increased myocardial L-carnitine concentration and greatly improved health and myocardial function. Withdrawal of L-carnitine supplementation from these dogs resulted in development of myocardial dysfunction and clinical signs of dilated cardiomyopathy.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/2019534/