Peer-reviewed veterinary case report
Swelling at vaccination site in horse - what could it be?
By Kannegieter, N J et al.·Published in Australian veterinary journal·2010·Roseville Equine Clinic, Australia·View original on PubMed →
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Original publication title: Myofibroblastic fibrosarcoma with multifocal osseous metaplasia at the site of equine influenza vaccination.
- Species:
- horse
Plain-English summary
A 12-year-old Quarterhorse x Arabian gelding developed a large swelling at the site of his equine influenza vaccination, which grew over six months. A biopsy revealed that the swelling was a fibrosarcoma, a type of tumor, measuring about 20 cm. Fortunately, there was no spread of the cancer to other parts of the body. The tumor was surgically removed, and the horse's wound healed well afterward. This case highlights a rare occurrence of a vaccine-related tumor in horses.
People also search for: horse vaccination lump · equine fibrosarcoma treatment · swelling after horse vaccine
Abstract
We describe a fibrosarcoma in a 12-year-old Quarterhorse x Arabian gelding as a sequela to equine influenza vaccination. Shortly after the second vaccination, swelling at the site was noticed by the owner and it continued to increase in size over the following 6 months. Biopsy of the mass indicated a fibrosarcoma had developed at the vaccination site. It was approximately 20 cm in diameter and elevated well above the level of the skin. There was no clinical evidence of metastases to the lungs or local lymph nodes. Surgical resection of the mass was performed and the wound healed by first and second intention. Histopathological examination and immunohistochemical staining confirmed a myofibroblastic fibrosarcoma with multifocal osseous metaplasia. To the authors' knowledge, this is the first equine case of a vaccine-associated fibrosarcoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20402700/