Peer-reviewed veterinary case report
Weakness and muscle loss in a 4-month-old collie-cross dog
By Rodenas, S et al.·Published in Journal of comparative pathology·2012·Southern Counties Veterinary Specialists, United Kingdom·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Myopathy associated with congenital fibre type disproportion in a young dog.
- Species:
- dog
Plain-English summary
A 4-month-old female collie-cross was brought to the vet because she was getting weaker, had trouble exercising, and was losing muscle mass. After tests, the vet found that she had a muscle condition called congenital fibre type disproportion, which means her muscle fibers were not developing properly. Unfortunately, despite the diagnosis, her condition continued to worsen over the next three months, and she was humanely euthanized due to her declining health.
People also search for: puppy weakness exercise intolerance · collie muscle disease · dog muscle atrophy treatment
Abstract
A 4-month-old, female collie-cross dog was presented for evaluation of slowly progressive weakness, exercise intolerance and muscle atrophy. Neurological examination and electrodiagnostic testing were consistent with a generalized myopathy or, less likely, an axonal polyneuropathy. Muscle biopsy samples revealed marked variability in myofibre size with scattered or clustered atrophic or hypotrophic type 1 fibres. Type 1 fibres were 65% smaller than type 2A fibres and the percentage of type 1 fibres exceeded reference values for both limb muscles examined. On the basis of the clinical evaluation, pathological changes and the absence of another defined congenital or acquired myopathy, a diagnosis of a myopathy associated with congenital fibre type disproportion was made. Three months later the animal was humanely euthanized because of worsening clinical signs.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22789857/