Peer-reviewed veterinary case report
Nasal cancer spread to bone causing lameness in two dogs
By Hahn, K A & Matlock, C L·Published in Journal of the American Veterinary Medical Association·1990·Department of Veterinary Clinical Sciences·View original on PubMed →
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Original publication title: Nasal adenocarcinoma metastatic to bone in two dogs.
- Species:
- dog
Plain-English summary
A 6-year-old neutered Golden Retriever and a 6-year-old spayed mixed-breed dog were both diagnosed with nasal adenocarcinoma (a type of nose cancer) after showing chronic nasal discharge that didn't improve with antibiotics. The Golden Retriever underwent surgery and radiation therapy, while the mixed-breed received chemotherapy with cisplatin. Unfortunately, both dogs later developed lameness due to the cancer spreading to their bones, which was confirmed through X-rays. Despite the initial treatments, the cancer had metastasized, indicating a serious progression of the disease.
People also search for: dog nasal cancer treatment · Golden Retriever lameness · mixed-breed dog chemotherapy side effects
Abstract
Diagnosis of nasal adenocarcinoma was made in a 6-year-old 35-kg neutered Golden Retriever and a 6-year-old 8-kg spayed mixed-breed dog with chronic bilateral nasal discharge unresponsive to antibiotics. Treatment for the Golden Retriever consisted of bilateral rhinotomy, curettage, and postoperative fractionated 48-Gy orthovoltage irradiation. The mixed-breed dog was treated with cisplatin. After complete remission of the primary neoplasm, the dogs were reevaluated because of acute lameness. Radiography of the right stifle of the Golden Retriever revealed soft tissue swelling, extensive bony destruction of the distal femoral metaphysis and epiphysis, and pathologic fracture involving the medial condyle. Radiography of the left scapula of the mixed-breed dog revealed lysis of the glenoid cavity and subchondral scapular bone. Diagnosis of metastatic carcinoma was made in both dogs. With treatment improvements and longer survival time of affected dogs, sinonasal neoplasia may be observed to develop in similar life-threatening metastatic sites.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/2211294/