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Peer-reviewed veterinary case report

Nasal MRSA bacteria found in dogs after cephalexin treatment

By Fungwithaya, Punpichaya et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2017·Department of Veterinary Microbiology·View original on PubMed

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Original publication title: Nasal carriage of methicillin-resistantin dogs treated with cephalexin monohydrate.

Species:
dog

Plain-English summary

Ten dogs with skin infections were treated with an antibiotic called cephalexin. Within a week of starting treatment, all the dogs developed a type of bacteria called methicillin-resistant Staphylococcus pseudintermedius (MRSP) in their noses, which can be hard to treat. Even after a year, some of these resistant bacteria were still present in the dogs. This means that using cephalexin may have encouraged the growth of these resistant bacteria, which could be a concern for their health and treatment options.

People also search for: dog skin infection treatment · cephalexin for dogs side effects · MRSP in dogs treatment

Abstract

This study aimed to investigate the nasal carriage of methicillin-resistant(MRSP) in dogs treated with oral cephalexin monohydrate. Ten dogs with superficial pyoderma were monitored longitudinally for carriage of MRSP for up to 1 year after treatment; the strains were typed and antibiograms were determined. Methicillin-susceptible(MSSP) was recovered prior to treatment in all dogs and could be isolated after 12 months in 1 dog. Methicillin-resistantwas detected within 1 week of treatment in all dogs, and 3 clones represented by ST45, ST112, and ST181 were consistently present for up to 12 months after treatment. All MRSP isolates were resistant to at least 7 common antimicrobials. Oral cephalexin monohydrate treatment selected for strains of multi-resistant MRSP, which were still present after 1 year.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28042159/