Peer-reviewed veterinary case report
Dog with nasal clear cell chondrosarcoma causing nosebleeds
By Moloney, Megan et al.·Published in Journal of comparative pathology·2024·Lumbry Park Veterinary Specialists, United Kingdom·View original on PubMed →
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Original publication title: Nasal clear cell chondrosarcoma in a dog.
- Species:
- dog
Plain-English summary
A 5-year-old male neutered crossbreed dog was brought in with a 6-8 week history of nosebleeds and nasal discharge. A CT scan revealed a tumor in the right nasal cavity, which was diagnosed as a clear cell chondrosarcoma, a rare type of cancer. The dog was treated with meloxicam, a pain relief medication, but unfortunately, the owners chose to euthanize the dog just 9 days after the diagnosis due to the severity of the condition.
People also search for: dog nosebleeds · dog nasal tumor treatment · clear cell chondrosarcoma in dogs
Abstract
An intranasal tumour was diagnosed in a 5-year-old male neutered crossbreed dog following a 6-8 week history of intermittent epistaxis and nasal discharge. Computed tomography identified a mass in the right nasal cavity. Histologically, the mass was composed of sheets and indistinct clusters of predominantly clear or vacuolated round to polygonal cells; periodic acid-Schiff staining revealed glycogen granules within some tumour cells. Immunohistochemical labelling revealed that the tumour cells were immunopositive for vimentin and S100 and negative for pancytokeratin, Melan-A and PNL2, supporting a diagnosis of a clear cell variant of chondrosarcoma (CCC). Although the dog was treated with meloxicam, the owners opted for euthanasia 9 days after presentation. Considering that there is only one other reported case of a suspected CCC in a dog, also in the nasal cavity, this could represent a species-specific predilection site of this rare canine neoplasm.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39047344/