Peer-reviewed veterinary case report
Nasal oncocytoma causing sneezing and swelling in a cat
By Doughty, R W et al.·Published in Veterinary pathology·2006·PCS Biology·View original on PubMed →
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Original publication title: Nasal oncocytoma in a domestic shorthair cat.
- Species:
- cat
Plain-English summary
A 12-year-old Domestic Shorthair cat was taken to the vet because of swelling around its eyes and sneezing. After examining a tissue sample, the vet found a type of tumor called an oncocytoma in the cat's nasal cavity. Fortunately, the tumor did not invade nearby blood vessels or lymph nodes, which is a good sign. The cat's condition was diagnosed through a biopsy, and while the treatment details are not specified, early detection is key for managing such tumors.
People also search for: cat nasal tumor symptoms · Domestic Shorthair sneezing · cat eye swelling treatment
Abstract
An oncocytoma was diagnosed in the nasal cavity of a 12-year-old Domestic Shorthair cat who presented with periocular swelling and sneezing. Histologic examination from biopsy material revealed monomorphic sheets, anastomosing cords, tubules, and acini composed of large polygonal to oval cells that contained abundant finely granular eosinophilic cytoplasm. No vascular or lymphatic invasions were noted. Histochemical stains revealed positive staining of tumor cells with periodic acid-Schiff (PAS) (before and after diastase digestion) and phosphotungstic acid-hematoxylin. Immunohistochemical evaluation of the tumor cells demonstrated positive staining for cytokeratin and negative staining for vimentin, desmin, S-100, glial fibrillar acidic protein, and neuronal specific enolase. Ultrastructurally, the tumor cells contained large numbers of mitochondria within their cytoplasm, which confirmed a diagnosis of oncocytoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16966454/