Peer-reviewed veterinary case report
Natural and experimental poisoning of goats with the pyrrolizidine alkaloid-producing plant Crotalaria retusa L.
- Journal:
- Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
- Year:
- 2013
- Authors:
- Maia, Lisanka A et al.
- Affiliation:
- Veterinary Hospital · Brazil
Abstract
Crotalaria retusa L. (rattleweed), estimated to contain about 4.96% monocrotaline (MCT) in the seed, was associated with a natural poisoning outbreak in goats. The poisoning was experimentally reproduced by the administration of C. retusa seeds containing approximately 4.49% of MCT. Thus, 1 of 3 goats given a single dose of 5 g/kg bodyweight (bw) of seeds (248 mg MCT/kg bw) and 2 goats given a single dose of 347 mg MCT/kg bw showed acute clinical signs and were euthanized 10-11 days after dosing. Clinical signs and gross and histologic lesions were characteristic of acute centrilobular liver necrosis.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/23847092/