Peer-reviewed veterinary case report
Cats with FIP have much higher feline coronavirus levels than healthy
By Kipar, Anja et al.·Published in Journal of feline medicine and surgery·2006·Institut fü, United Kingdom·View original on PubMed →
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Original publication title: Natural FCoV infection: cats with FIP exhibit significantly higher viral loads than healthy infected cats.
- Species:
- cat
Plain-English summary
A group of cats with feline infectious peritonitis (FIP) had much higher levels of the feline coronavirus (FCoV) in their bodies compared to healthy cats that were also infected with the virus. This suggests that cats with FIP may struggle more with clearing the virus from their system, leading to more severe illness. Understanding these viral loads could help veterinarians better assess and manage FIP in affected cats.
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Abstract
Natural feline coronavirus (FCoV) infection has been shown to not only induce intestinal infection with viral shedding, but also systemic infection which either remains without clinical signs or leads to feline infectious peritonitis (FIP). As systemic infection is not the key event in the development of FIP, the question arises as to whether a potential difference in viral load might be of importance. Therefore, the purpose of this study was to quantitatively assess feline coronavirus (FCoV) RNA loads in haemolymphatic tissues of healthy, long-term FCoV-infected cats and cats with FIP. In cats that died from FIP, viral loads were significantly higher, indicating a higher rate of viral replication or a reduced capacity for viral clearance in cats developing and/or suffering from FIP.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16213766/