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Peer-reviewed veterinary case report

Survival and severity of subaortic stenosis in 166 dogs

By Eason, B D et al.·Published in Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology·2021·University of Missouri, United States·View original on PubMed

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Original publication title: Natural history of subaortic stenosis in 166 dogs (1999-2011).

Species:
dog

Plain-English summary

A group of 166 dogs with a heart condition called subaortic stenosis (SAS) was studied to understand how long they might live based on the severity of their condition. The dogs were divided into four groups based on the pressure in their hearts, with those having very severe SAS (pressure over 130 mmHg) having the shortest median survival time of just 3 years. In contrast, dogs with mild SAS lived an average of 10.6 years. The study suggests that the severity of SAS significantly impacts how long dogs can expect to live, with earlier diagnosis leading to better outcomes.

People also search for: dog heart disease survival · subaortic stenosis in dogs · dog heart condition treatment · how long do dogs live with heart problems · symptoms of subaortic stenosis in dogs

Abstract

INTRODUCTION: Subaortic stenosis (SAS) is one of the most common congenital cardiac diseases in dogs. The objective of this study was to provide survival times on a large population of dogs with SAS and to propose a redefined pressure gradient (PG) scale to include a mild, moderate, severe and very severe disease group. ANIMALS, MATERIALS AND METHODS: Dogs were divided into four groups based on the Doppler-derived PG across the stenosis. Disease severity was defined as follows: mild&#xa0;=&#xa0;PG&#xa0;<&#xa0;50&#xa0;mmHg; moderate&#xa0;=&#xa0;PG range 50-80&#xa0;mmHg; severe&#xa0;=&#xa0;PG range 80-130&#xa0;mmHg; and very severe&#xa0;=&#xa0;PG&#xa0;>&#xa0;130&#xa0;mmHg. Over the study period (1999-2011), 166 client-owned dogs were diagnosed with SAS of which 129 had follow-up information available. RESULTS: Unadjusted median survival time for severity groups were as follows: mild 10.6 years; moderate 9.9 years; severe 7.3 years; and very severe 3.0 years. Univariable analysis examining the effect of the PG, age at diagnosis&#xa0;and sex found only the PG and age at diagnosis had a significant effect on survival. Adjusted survival curves showed that the survival time in the very severe group was decreased compared with all other groups. CONCLUSION: Based on the results of this study, a revised SAS classification system with four PG groups is appropriate. Dogs with a PG&#xa0;>&#xa0;130&#xa0;mmHg were identified as those with the lowest median survival time.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34634578/