Peer-reviewed veterinary case report
Puppy with natural systemic canine distemper virus infection signs
By Headley, Selwyn A. & Sukura, AnttiĀ·Published in Brazilian Journal of Veterinary PathologyĀ·2009Ā·View original on Crossref ā
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Original publication title: Naturally occurring systemic canine distemper virus infection in a pup
- Species:
- dog
Plain-English summary
A 4-month-old puppy was diagnosed with a serious infection caused by the canine distemper virus (CDV), which led to symptoms like swollen footpads and pneumonia. The puppy had a runny nose and showed signs of severe lung infection on X-rays. Tests revealed that the virus was affecting multiple organs, including the heart and liver. Unfortunately, this infection can be quite severe, and treatment typically focuses on supportive care, but the prognosis can vary depending on the extent of the disease.
People also search for: puppy distemper symptoms Ā· dog pneumonia treatment Ā· canine distemper virus signs
Abstract
This report describes the pathologic and immunohistochemical findings associated with naturally occurring systemic canine distemper virus (CDV) infection in a dog. Clinically, there was lymphopenia and hyperkeratosis of footpads, while pneumonia was identified by radiology. Gross lesions consisted of bilateral ocular discharge and discrete digital hyperkeratosis. By histopathology, there was severe interstitial pneumonia and necrosis of splenic germinal centers. Additionally, eosinophilic intranuclear inclusion bodies were observed within cerebellar astrocytes without marked manifestation of CDV-induced encephalitis. Further, intracytoplasmic bodies were identified within the epithelial cells of the renal pelvis, lung, and urinary bladder. Immunohistochemistry identified the presence of CDV antigens in these tissues and further confirmed the systemic infection to the epidermis of footpads, heart, liver, intestine, spleen, and lymph node.
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Search related cases āOriginal publication on Crossref: https://doi.org/10.24070/bjvp.1983-0246.002017