Peer-reviewed veterinary case report
Behavior changes and seizures from brain necrosis in two cats
By Brini, E et al.·Published in Journal of feline medicine and surgery·2004·Department of Veterinary Clinical Sciences, Italy·View original on PubMed →
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Original publication title: Necrosis of hippocampus and piriform lobe: clinical and neuropathological findings in two Italian cats.
- Species:
- cat
Plain-English summary
Two Italian cats were brought to the vet because they suddenly started showing unusual behavior and having complex partial seizures. Despite normal blood tests and a CT scan that didn't show any issues, their condition worsened even after treatment with diazepam (Valium). Unfortunately, both cats were ultimately euthanized due to the severity of their symptoms, and a post-mortem examination revealed damage in the brain areas responsible for their behavior and seizures.
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Abstract
The present paper reports the clinical and neuropathological findings in two cats with a neuropathologically confirmed diagnosis of necrosis of the hippocampus and piriform lobe. The cats were presented because of acute onset of behavioural changes and complex partial seizures. The neurological examination suggested a forebrain lesion. The results of blood examination were within the normal range, and the cerebrospinal fluid (CSF) analysis and computed tomography (CT) scan in one cat did not show any abnormality. Despite therapy with diazepam (Valium; Roche) there was deterioration of the clinical signs and the cats were euthanased. The neuropathological examination revealed hippocampal necrosis that included the piriform lobe.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/15546770/