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Peer-reviewed veterinary case report

Cats with sudden seizures and brain tissue death in hippocampus

By Brini, E. et al.·Published in Journal of Feline Medicine and Surgery·2004·Department of Veterinary Clinical Sciences, University of Bologna, Via Tolara di Sopra 50, 40064 Ozzano, Emilia, Italy, Italy·View original on Crossref

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Original publication title: Necrosis of hippocampus and piriform lobe: Clinical and neuropathological findings in two italian cats

Species:
cat
Brain & nervesCats

Plain-English summary

Two Italian cats were brought to the vet because they suddenly started showing unusual behavior and having complex partial seizures. A neurological exam suggested a problem in the brain, but blood tests and a CT scan didn't show any issues. The cats were treated with diazepam (Valium) to help with the seizures, but their condition worsened, leading to the difficult decision to euthanize them. A later examination of their brains revealed necrosis (death of brain tissue) in the hippocampus and piriform lobe.

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Abstract

The present paper reports the clinical and neuropathological findings in two cats with a neuropathologically confirmed diagnosis of necrosis of the hippocampus and piriform lobe. The cats were presented because of acute onset of behavioural changes and complex partial seizures. The neurological examination suggested a forebrain lesion. The results of blood examination were within the normal range, and the cerebrospinal fluid (CSF) analysis and computed tomography (CT) scan in one cat did not show any abnormality. Despite therapy with diazepam (Valium®; Roche) there was deterioration of the clinical signs and the cats were euthanased. The neuropathological examination revealed hippocampal necrosis that included the piriform lobe.

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Original publication on Crossref: https://doi.org/10.1016/j.jfms.2003.12.007