Peer-reviewed veterinary case report
Needle-free delivery of an inactivated avian influenza H5N3 virus vaccine elicits potent antibody responses in chickens.
- Journal:
- Canadian journal of veterinary research = Revue canadienne de recherche veterinaire
- Year:
- 2013
- Authors:
- Ogunremi, Oladele et al.
- Affiliation:
- Ottawa Laboratory Fallowfield
- Species:
- bird
Abstract
A needle-free delivery system was assessed as a route for providing quick, safe, and effective vaccination against avian influenza (AI). Two groups of chickens were vaccinated with a commercially available inactivated H5N3 virus vaccine delivered either with a needle-free device or with the conventional syringe-and-needle method recommended by the vaccine manufacturer. The kinetic aspects of seroconversion, peak antibody levels, and antibody titers were measured by a combination of an indirect enzyme-linked immunosorbent assay and the hemagglutination-inhibition test and were all found to be similar in the 2 groups of chickens. We conclude that the needle-free delivery system could result in effective immunization against H5N1 AI epidemics and pandemics in chickens.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/24124275/