Peer-reviewed veterinary case report
How prostate enlargement lowers fertility in dogs
By Domosławska-Wyderska, Anna et al.·Published in Frontiers in veterinary science·2025·Department of Animal Reproduction with Clinic·View original on PubMed →
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Original publication title: Negative impact of benign prostatic hyperplasia on fertility in dogs-a mini-review.
- Species:
- dog
Plain-English summary
A male dog with fertility issues may be suffering from benign prostatic hyperplasia (BPH), a common condition that affects the prostate gland and can lead to poor semen quality. This condition often occurs alongside chronic prostatitis, which can further decrease fertility. To help restore fertility, veterinarians may recommend treatments like osaterone acetate or finasteride to reduce the size of the prostate and alleviate symptoms. Additionally, using antibiotics that can penetrate the prostate and antioxidants for support can be beneficial. With proper treatment, many dogs can regain their fertility.
People also search for: dog fertility problems · benign prostatic hyperplasia treatment in dogs · osaterone acetate for dogs · finasteride for dog prostate issues
Abstract
The aim of this article is to provide a comprehensive review of the negative impact of benign prostatic hyperplasia (BPH) on fertility in dogs. BPH is the most common disease of the prostate gland and one of the major causes of infertility in dogs, associated with impaired semen quality. Hormonal imbalance, oxidative stress, biochemical changes in prostatic fluid and haematospermia have been discussed as causes of reduced semen quality in dogs with BPH. Chronic prostatitis often occurs concurrently with BPH and has an additive negative effect on semen quality and fertility. In breeding dogs with infertility associated with BPH, treatment with the anti-androgen osaterone acetate or the 5α-reductase inhibitor finasteride is recommended to reduce prostate size and clinical symptoms and to restore fertility. Combined occurrence of BPH and chronic prostatitis requires simultaneous treatment of both conditions, including microbials with good penetration into the prostate. The use of antioxidants in the supportive treatment of BPH seems reasonable.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40417369/